Supervised prediction of drug-induced nephrotoxicity based on interleukin-6 and -8 expression levels

BACKGROUND: Drug-induced nephrotoxicity causes acute kidney injury and chronic kidney diseases, and is a major reason for late-stage failures in the clinical trials of new drugs. Therefore, early, pre-clinical prediction of nephrotoxicity could help to prioritize drug candidates for further evaluati...

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Detalles Bibliográficos
Autores principales: Su, Ran, Li, Yao, Zink, Daniele, Loo, Lit-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290648/
https://www.ncbi.nlm.nih.gov/pubmed/25521947
http://dx.doi.org/10.1186/1471-2105-15-S16-S16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290648/
https://www.ncbi.nlm.nih.gov/pubmed/25521947
http://dx.doi.org/10.1186/1471-2105-15-S16-S16

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