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Supervised prediction of drug-induced nephrotoxicity based on interleukin-6 and -8 expression levels

BACKGROUND: Drug-induced nephrotoxicity causes acute kidney injury and chronic kidney diseases, and is a major reason for late-stage failures in the clinical trials of new drugs. Therefore, early, pre-clinical prediction of nephrotoxicity could help to prioritize drug candidates for further evaluati...

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Detalles Bibliográficos
Autores principales:	Su, Ran, Li, Yao, Zink, Daniele, Loo, Lit-Hsin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290648/ https://www.ncbi.nlm.nih.gov/pubmed/25521947 http://dx.doi.org/10.1186/1471-2105-15-S16-S16

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