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An investigation of biomarkers derived from legacy microarray data for their utility in the RNA-seq era

BACKGROUND: Gene expression microarray has been the primary biomarker platform ubiquitously applied in biomedical research, resulting in enormous data, predictive models, and biomarkers accrued. Recently, RNA-seq has looked likely to replace microarrays, but there will be a period where both technol...

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Detalles Bibliográficos
Autores principales: Su, Zhenqiang, Fang, Hong, Hong, Huixiao, Shi, Leming, Zhang, Wenqian, Zhang, Wenwei, Zhang, Yanyan, Dong, Zirui, Lancashire, Lee J, Bessarabova, Marina, Yang, Xi, Ning, Baitang, Gong, Binsheng, Meehan, Joe, Xu, Joshua, Ge, Weigong, Perkins, Roger, Fischer, Matthias, Tong, Weida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290828/
https://www.ncbi.nlm.nih.gov/pubmed/25633159
http://dx.doi.org/10.1186/s13059-014-0523-y