Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy

Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian...

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Autores principales: De Smet, Birgit, Sarovich, Derek S., Price, Erin P., Mayo, Mark, Theobald, Vanessa, Kham, Chun, Heng, Seiha, Thong, Phe, Holden, Matthew T. G., Parkhill, Julian, Peacock, Sharon J., Spratt, Brian G., Jacobs, Jan A., Vandamme, Peter, Currie, Bart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290968/
https://www.ncbi.nlm.nih.gov/pubmed/25392354
http://dx.doi.org/10.1128/JCM.02574-14
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author De Smet, Birgit
Sarovich, Derek S.
Price, Erin P.
Mayo, Mark
Theobald, Vanessa
Kham, Chun
Heng, Seiha
Thong, Phe
Holden, Matthew T. G.
Parkhill, Julian
Peacock, Sharon J.
Spratt, Brian G.
Jacobs, Jan A.
Vandamme, Peter
Currie, Bart J.
author_facet De Smet, Birgit
Sarovich, Derek S.
Price, Erin P.
Mayo, Mark
Theobald, Vanessa
Kham, Chun
Heng, Seiha
Thong, Phe
Holden, Matthew T. G.
Parkhill, Julian
Peacock, Sharon J.
Spratt, Brian G.
Jacobs, Jan A.
Vandamme, Peter
Currie, Bart J.
author_sort De Smet, Birgit
collection PubMed
description Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy.
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spelling pubmed-42909682015-01-26 Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy De Smet, Birgit Sarovich, Derek S. Price, Erin P. Mayo, Mark Theobald, Vanessa Kham, Chun Heng, Seiha Thong, Phe Holden, Matthew T. G. Parkhill, Julian Peacock, Sharon J. Spratt, Brian G. Jacobs, Jan A. Vandamme, Peter Currie, Bart J. J Clin Microbiol Epidemiology Burkholderia pseudomallei isolates with shared multilocus sequence types (STs) have not been isolated from different continents. We identified two STs shared between Australia and Cambodia. Whole-genome analysis revealed substantial diversity within STs, correctly identified the Asian or Australian origin, and confirmed that these shared STs were due to homoplasy. American Society for Microbiology 2014-12-18 2015-01 /pmc/articles/PMC4290968/ /pubmed/25392354 http://dx.doi.org/10.1128/JCM.02574-14 Text en Copyright © 2015, De Smet et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Epidemiology
De Smet, Birgit
Sarovich, Derek S.
Price, Erin P.
Mayo, Mark
Theobald, Vanessa
Kham, Chun
Heng, Seiha
Thong, Phe
Holden, Matthew T. G.
Parkhill, Julian
Peacock, Sharon J.
Spratt, Brian G.
Jacobs, Jan A.
Vandamme, Peter
Currie, Bart J.
Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy
title Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy
title_full Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy
title_fullStr Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy
title_full_unstemmed Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy
title_short Whole-Genome Sequencing Confirms that Burkholderia pseudomallei Multilocus Sequence Types Common to Both Cambodia and Australia Are Due to Homoplasy
title_sort whole-genome sequencing confirms that burkholderia pseudomallei multilocus sequence types common to both cambodia and australia are due to homoplasy
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4290968/
https://www.ncbi.nlm.nih.gov/pubmed/25392354
http://dx.doi.org/10.1128/JCM.02574-14
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