Functional Variants in DPYSL2 Sequence Increase Risk of Schizophrenia and Suggest a Link to mTOR Signaling

Numerous linkage and association studies by our group and others have implicated DPYSL2 at 8p21.2 in schizophrenia. Here we explore DPYSL2 for functional variation that underlies these associations. We sequenced all 14 exons of DPYSL2 as well as 27 conserved noncoding regions at the locus in 137 cas...

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Detalles Bibliográficos
Autores principales: Liu, Yaping, Pham, Xuan, Zhang, Lilei, Chen, Pei-lung, Burzynski, Grzegorz, McGaughey, David M., He, Shan, McGrath, John A., Wolyniec, Paula, Fallin, Margaret D., Pierce, Megan S., McCallion, Andrew S., Pulver, Ann E., Avramopoulos, Dimitrios, Valle, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291470/
https://www.ncbi.nlm.nih.gov/pubmed/25416705
http://dx.doi.org/10.1534/g3.114.015636

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