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β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer

Cancer stem cells (CSCs) are responsible for tumor initiation and progression. Toll-like receptors (TLRs) are highly expressed in cancer cells and associated with poor prognosis. However, a linkage between CSCs and TLRs is unclear, and potential intervention strategies to prevent TLR stimulation-ind...

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Detalles Bibliográficos
Autores principales: Jia, D, Yang, W, Li, L, Liu, H, Tan, Y, Ooi, S, Chi, L, Filion, L G, Figeys, D, Wang, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291491/
https://www.ncbi.nlm.nih.gov/pubmed/25257174
http://dx.doi.org/10.1038/cdd.2014.145