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β-Catenin and NF-κB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer
Cancer stem cells (CSCs) are responsible for tumor initiation and progression. Toll-like receptors (TLRs) are highly expressed in cancer cells and associated with poor prognosis. However, a linkage between CSCs and TLRs is unclear, and potential intervention strategies to prevent TLR stimulation-ind...
Autores principales: | Jia, D, Yang, W, Li, L, Liu, H, Tan, Y, Ooi, S, Chi, L, Filion, L G, Figeys, D, Wang, L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291491/ https://www.ncbi.nlm.nih.gov/pubmed/25257174 http://dx.doi.org/10.1038/cdd.2014.145 |
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