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MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

Innate immune receptors for pathogen- and damage-associated molecular patterns (PAMPs and DAMPs) orchestrate inflammatory responses to infection and injury. Secreted by activated immune cells or passively released by damaged cells, HMGB1 is subjected to redox modification that distinctly influences...

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Detalles Bibliográficos
Autores principales:	Yang, Huan, Wang, Haichao, Ju, Zhongliang, Ragab, Ahmed A., Lundbäck, Peter, Long, Wei, Valdes-Ferrer, Sergio I., He, Mingzhu, Pribis, John P., Li, Jianhua, Lu, Ben, Gero, Domokos, Szabo, Csaba, Antoine, Daniel J., Harris, Helena E., Golenbock, Doug T., Meng, Jianmin, Roth, Jesse, Chavan, Sangeeta S., Andersson, Ulf, Billiar, Timothy R., Tracey, Kevin J., Al-Abed, Yousef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291531/ https://www.ncbi.nlm.nih.gov/pubmed/25559892 http://dx.doi.org/10.1084/jem.20141318

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