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Hyper-Inflammation and Skin Destruction Mediated by Rosiglitazone Activation of Macrophages in IL-6 Deficiency
Injury initiates recruitment of macrophages to support tissue repair; however, excessive macrophage activity may exacerbate tissue damage causing further destruction and subsequent delay in wound repair. Here we show that the peroxisome proliferation–activated receptor-γ agonist, rosiglitazone (Rosi...
Autores principales: | Das, Lopa M, Rosenjack, Julie, Au, Liemin, Galle, Pia S, Hansen, Morten B, Cathcart, Martha K, McCormick, Thomas S, Cooper, Kevin D, Silverstein, Roy L, Lu, Kurt Q |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291681/ https://www.ncbi.nlm.nih.gov/pubmed/25184961 http://dx.doi.org/10.1038/jid.2014.375 |
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