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Highly Enantioselective, Intermolecular Hydroamination of Allenyl Esters Catalyzed by Bifunctional Phosphinothioureas

[Image: see text] Bifunctional phosphinothiourea catalysts have been developed successfully for the highly regio- and enantioselective γ-hydroamination of allenyl and propargyl esters with N-methoxy carbamate nucleophiles to yield α,β-unsaturated γ-amino acid ester products. In the case of propargyl...

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Detalles Bibliográficos
Autores principales:	Fang, Yuan-Qing, Tadross, Pamela M., Jacobsen, Eric N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291748/ https://www.ncbi.nlm.nih.gov/pubmed/25496451 http://dx.doi.org/10.1021/ja5117638

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