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Pretargeted Imaging and Radioimmunotherapy of Cancer Using Antibodies and Bioorthogonal Chemistry
Selective delivery of radionuclides to tumors may be accomplished using a two-step approach, in which in the first step the tumor is pretargeted with an unlabeled antibody construct and in the second step the tumor is targeted with a radiolabeled small molecule. This results in a more rapid clearanc...
Autores principales: | van de Watering, Floor C. J., Rijpkema, Mark, Robillard, Marc, Oyen, Wim J. G., Boerman, Otto C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292049/ https://www.ncbi.nlm.nih.gov/pubmed/25593917 http://dx.doi.org/10.3389/fmed.2014.00044 |
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