Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors

Detalles Bibliográficos
Autores principales: Horton, Brendan, Spranger, Stefani, Williams, Jason, Gajewski, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Poster Presentation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292434/
http://dx.doi.org/10.1186/2051-1426-2-S3-P213
_version_ 1782352484318052352
author Horton, Brendan
Spranger, Stefani
Williams, Jason
Gajewski, Thomas
author_facet Horton, Brendan
Spranger, Stefani
Williams, Jason
Gajewski, Thomas
author_sort Horton, Brendan
collection PubMed
description
format Online
Article
Text
id pubmed-4292434
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-42924342015-01-15 Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors Horton, Brendan Spranger, Stefani Williams, Jason Gajewski, Thomas J Immunother Cancer Poster Presentation BioMed Central 2014-11-06 /pmc/articles/PMC4292434/ http://dx.doi.org/10.1186/2051-1426-2-S3-P213 Text en Copyright © 2014 Horton et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Poster Presentation
Horton, Brendan
Spranger, Stefani
Williams, Jason
Gajewski, Thomas
Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors
title Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors
title_full Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors
title_fullStr Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors
title_full_unstemmed Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors
title_short Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors
title_sort agonistic 4-1bb antibodies in combination with inhibitory antibodies against ctla-4, pd-l1 or lag-3 act on cd8+ t cells in the tumor microenvironment and synergize to promote regression of established tumors
topic Poster Presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292434/
http://dx.doi.org/10.1186/2051-1426-2-S3-P213
work_keys_str_mv AT hortonbrendan agonistic41bbantibodiesincombinationwithinhibitoryantibodiesagainstctla4pdl1orlag3actoncd8tcellsinthetumormicroenvironmentandsynergizetopromoteregressionofestablishedtumors
AT sprangerstefani agonistic41bbantibodiesincombinationwithinhibitoryantibodiesagainstctla4pdl1orlag3actoncd8tcellsinthetumormicroenvironmentandsynergizetopromoteregressionofestablishedtumors
AT williamsjason agonistic41bbantibodiesincombinationwithinhibitoryantibodiesagainstctla4pdl1orlag3actoncd8tcellsinthetumormicroenvironmentandsynergizetopromoteregressionofestablishedtumors
AT gajewskithomas agonistic41bbantibodiesincombinationwithinhibitoryantibodiesagainstctla4pdl1orlag3actoncd8tcellsinthetumormicroenvironmentandsynergizetopromoteregressionofestablishedtumors

Ejemplares similares