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Evidence of synergy with combined BRAF-targeted therapy and immune checkpoint blockade for metastatic melanoma
Significant advances in the treatment of melanoma have been made with BRAF-targeted therapy and immune checkpoint blockade, and these strategies are now being combined empirically in clinical trials. Potential synergy is demonstrated in murine models and in analysis of longitudinal biopsies from pat...
Autores principales: | Cooper, Zachary A, Reuben, Alexandre, Amaria, Rodabe N, Wargo, Jennifer A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292518/ https://www.ncbi.nlm.nih.gov/pubmed/25941608 http://dx.doi.org/10.4161/21624011.2014.954956 |
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