Cargando…
The human CD40 agonistic antibody ADC-1013 generates immune mediated anti-tumor effects in syngeneic tumor models in hCD40 transgenic mice
Autores principales: | Mangsbo, Sara M, Veitonmäki, Niina, Gustfson, Erika, Smith, Karin Enell, Furebring, Christina, Norlén, Per, Lindstedt, Malin, Tötterman, Thomas H, Ellmark, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292546/ http://dx.doi.org/10.1186/2051-1426-2-S3-P251 |
Ejemplares similares
-
Pre-clinical development of the human CD40 agonistic antibody ADC-1013
por: Norlén, Per, et al.
Publicado: (2015) -
ADC-1013, an agonistic CD40 antibody optimized for local immunotherapy of cancer
por: Mangsbo, Sara M, et al.
Publicado: (2013) -
Kick-starting the cancer-immunity cycle by targeting CD40
por: Ellmark, P, et al.
Publicado: (2015) -
Tumor-directed immunotherapy can generate tumor-specific T cell responses through localized co-stimulation
por: Ellmark, Peter, et al.
Publicado: (2016) -
The human anti-CD40 agonist antibody mitazalimab (ADC-1013; JNJ-64457107) activates antigen-presenting cells, improves expansion of antigen-specific T cells, and enhances anti-tumor efficacy of a model cancer vaccine in vivo
por: Deronic, Adnan, et al.
Publicado: (2021)