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Markov chain Monte Carlo based analysis of post-translationally modified VDAC gating kinetics

The voltage-dependent anion channel (VDAC) is the main conduit for permeation of solutes (including nucleotides and metabolites) of up to 5 kDa across the mitochondrial outer membrane (MOM). Recent studies suggest that VDAC activity is regulated via post-translational modifications (PTMs). Yet the n...

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Detalles Bibliográficos
Autores principales:	Tewari, Shivendra G., Zhou, Yifan, Otto, Bradley J., Dash, Ranjan K., Kwok, Wai-Meng, Beard, Daniel A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292549/ https://www.ncbi.nlm.nih.gov/pubmed/25628567 http://dx.doi.org/10.3389/fphys.2014.00513

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