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Neutropenia: occurrence and management in women with breast cancer receiving chemotherapy

OBJECTIVES: to identify the prevalence, and describe the management of, neutropenia throughout the chemotherapy treatment among women with breast cancer. METHODS: observational study, cycles of chemotherapy. 116 neutropenic events were recorded, and 63.3% of the patients presented neutropenia at som...

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Detalles Bibliográficos
Autores principales: do Nascimento, Talita Garcia, de Andrade, Marceila, de Oliveira, Rosemeire Aparecida, de Almeida, Ana Maria, Gozzo, Thais de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292595/
https://www.ncbi.nlm.nih.gov/pubmed/26107839
http://dx.doi.org/10.1590/0104-1169.3305.2416
Descripción
Sumario:OBJECTIVES: to identify the prevalence, and describe the management of, neutropenia throughout the chemotherapy treatment among women with breast cancer. METHODS: observational study, cycles of chemotherapy. 116 neutropenic events were recorded, and 63.3% of the patients presented neutropenia at some point of their treatment, 46.5% of these presenting grade II. The management used was temporary suspension between the cycles and the mean number of delays was 6 days. The study was prospective and longitudinal, where the evaluation of the hematological toxicities was undertaken at each cycle of chemotherapy, whether neoadjuvant or adjuvant. RESULTS: 79 women were included, who received 572 cycles. However, the reasons for the suspensions were the lack of a space in the chemotherapy center, followed by neutropenia. CONCLUSION: neutropenia is one of the most common and serious adverse events observed during the chemotherapy. Nursing must invest in research regarding this adverse event and in management strategies for organizing the public health system, so as to offer quality care.