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Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program

OBJECTIVES: to survey the prevalence of human papillomavirus, associated risk factors and genotype distribution in women who were referred to cervical cancer screening when attended in a Family Health Program. METHOD: we conducted a cross-sectional survey, investigating 351 women. Polymerase chain r...

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Autores principales: Augusto, Everton Faccini, dos Santos, Larissa Silva, Oliveira, Ledy do Horto dos Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292707/
https://www.ncbi.nlm.nih.gov/pubmed/24553709
http://dx.doi.org/10.1590/0104-1169.3189.2398
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author Augusto, Everton Faccini
dos Santos, Larissa Silva
Oliveira, Ledy do Horto dos Santos
author_facet Augusto, Everton Faccini
dos Santos, Larissa Silva
Oliveira, Ledy do Horto dos Santos
author_sort Augusto, Everton Faccini
collection PubMed
description OBJECTIVES: to survey the prevalence of human papillomavirus, associated risk factors and genotype distribution in women who were referred to cervical cancer screening when attended in a Family Health Program. METHOD: we conducted a cross-sectional survey, investigating 351 women. Polymerase chain reaction for DNA amplification and restriction fragment length polymorphism analysis were used to detect and typify the papillomavirus. RESULTS: virus infection was detected in 8.8% of the samples. Among the 21 different genotypes identified in this study, 14 were high risk for cervical cancer, and the type 16 was the most prevalent type. The infection was associated with women who had non-stable sexual partners. Low risk types were associated with younger women, while the high risk group was linked to altered cytology. CONCLUSION: in this sample attended a Family Health Program, we found a low rate of papillomavirus infection. Virus frequency was associated to sexual behavior. However, the broad range of genotypes detected deserves attention regarding the vaccine coverage, which includes only HPV prevalent types.
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spelling pubmed-42927072015-01-26 Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program Augusto, Everton Faccini dos Santos, Larissa Silva Oliveira, Ledy do Horto dos Santos Rev Lat Am Enfermagem Original Articles OBJECTIVES: to survey the prevalence of human papillomavirus, associated risk factors and genotype distribution in women who were referred to cervical cancer screening when attended in a Family Health Program. METHOD: we conducted a cross-sectional survey, investigating 351 women. Polymerase chain reaction for DNA amplification and restriction fragment length polymorphism analysis were used to detect and typify the papillomavirus. RESULTS: virus infection was detected in 8.8% of the samples. Among the 21 different genotypes identified in this study, 14 were high risk for cervical cancer, and the type 16 was the most prevalent type. The infection was associated with women who had non-stable sexual partners. Low risk types were associated with younger women, while the high risk group was linked to altered cytology. CONCLUSION: in this sample attended a Family Health Program, we found a low rate of papillomavirus infection. Virus frequency was associated to sexual behavior. However, the broad range of genotypes detected deserves attention regarding the vaccine coverage, which includes only HPV prevalent types. Escola de Enfermagem de Ribeirão Preto / Universidade de São Paulo 2014 /pmc/articles/PMC4292707/ /pubmed/24553709 http://dx.doi.org/10.1590/0104-1169.3189.2398 Text en Copyright © 2014 Revista Latino-Americana de Enfermagem http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (CC BY-NC). This license lets others distribute, remix, tweak, and build upon your work non-commercially, and although their new works must also acknowledge you and be non-commercial, they don’t have to license their derivative works on the same terms.
spellingShingle Original Articles
Augusto, Everton Faccini
dos Santos, Larissa Silva
Oliveira, Ledy do Horto dos Santos
Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program
title Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program
title_full Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program
title_fullStr Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program
title_full_unstemmed Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program
title_short Human papillomavirus detection in cervical scrapes from women attended in the Family Health Program
title_sort human papillomavirus detection in cervical scrapes from women attended in the family health program
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292707/
https://www.ncbi.nlm.nih.gov/pubmed/24553709
http://dx.doi.org/10.1590/0104-1169.3189.2398
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