Using α radiation to boost cancer immunity?

Radioimmunotherapy aims to deliver radiation directly to cancer cells by means of a tumor specific vector coupled to a radionuclide. Alpha radionuclides are very potent agents to treat disseminated cancer and metastasis. We have demonstrated that α radiation can also induce immunogenic cell death, r...

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Detalles Bibliográficos
Autores principales: Gorin, Jean-Baptiste, Guilloux, Yannick, Morgenstern, Alfred, Chérel, Michel, Davodeau, François, Gaschet, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292714/
https://www.ncbi.nlm.nih.gov/pubmed/25941605
http://dx.doi.org/10.4161/21624011.2014.954925
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author Gorin, Jean-Baptiste
Guilloux, Yannick
Morgenstern, Alfred
Chérel, Michel
Davodeau, François
Gaschet, Joëlle
author_facet Gorin, Jean-Baptiste
Guilloux, Yannick
Morgenstern, Alfred
Chérel, Michel
Davodeau, François
Gaschet, Joëlle
author_sort Gorin, Jean-Baptiste
collection PubMed
description Radioimmunotherapy aims to deliver radiation directly to cancer cells by means of a tumor specific vector coupled to a radionuclide. Alpha radionuclides are very potent agents to treat disseminated cancer and metastasis. We have demonstrated that α radiation can also induce immunogenic cell death, reinforcing interest in their clinical development.
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spelling pubmed-42927142015-12-06 Using α radiation to boost cancer immunity? Gorin, Jean-Baptiste Guilloux, Yannick Morgenstern, Alfred Chérel, Michel Davodeau, François Gaschet, Joëlle Oncoimmunology Article Radioimmunotherapy aims to deliver radiation directly to cancer cells by means of a tumor specific vector coupled to a radionuclide. Alpha radionuclides are very potent agents to treat disseminated cancer and metastasis. We have demonstrated that α radiation can also induce immunogenic cell death, reinforcing interest in their clinical development. Taylor & Francis 2014-12-06 /pmc/articles/PMC4292714/ /pubmed/25941605 http://dx.doi.org/10.4161/21624011.2014.954925 Text en © 2014 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Article
Gorin, Jean-Baptiste
Guilloux, Yannick
Morgenstern, Alfred
Chérel, Michel
Davodeau, François
Gaschet, Joëlle
Using α radiation to boost cancer immunity?
title Using α radiation to boost cancer immunity?
title_full Using α radiation to boost cancer immunity?
title_fullStr Using α radiation to boost cancer immunity?
title_full_unstemmed Using α radiation to boost cancer immunity?
title_short Using α radiation to boost cancer immunity?
title_sort using α radiation to boost cancer immunity?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292714/
https://www.ncbi.nlm.nih.gov/pubmed/25941605
http://dx.doi.org/10.4161/21624011.2014.954925
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AT gaschetjoelle usingaradiationtoboostcancerimmunity

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