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Involvement of the nuclear factor-κB signaling pathway in the regulation of CXC chemokine receptor-4 expression in neuroblastoma cells induced by tumor necrosis factor-α

Metastasis is a hallmark of malignant neuroblastoma and is the main reason for therapeutic failure and recurrence of the tumor. The CXC chemokine receptor-4 (CXCR4), a Gi protein-coupled receptor for the ligand CXCL12/stromal cell-derived factor-1α (SDF-1α), is expressed in various types of tumor. T...

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Detalles Bibliográficos
Autores principales: ZHI, YUNLAI, LU, HONGTING, DUAN, YUHE, SUN, WEISHENG, GUAN, GE, DONG, QIAN, YANG, CHUANMIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292717/
https://www.ncbi.nlm.nih.gov/pubmed/25503960
http://dx.doi.org/10.3892/ijmm.2014.2032