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Contribution of non-reference alleles in mtDNA of Alzheimer's disease patients
Many observations suggest that mutations of mitochondrial DNA (mtDNA) could be responsible for the neurodegenerative changes of Alzheimer's disease (AD). Here we examined the signal intensity of the four alleles of each mtDNA nucleotide position (np) in whole blood of AD patients and age-matche...
Autores principales: | Casoli, Tiziana, Di Stefano, Giuseppina, Spazzafumo, Liana, Balietti, Marta, Giorgetti, Belinda, Giuli, Cinzia, Postacchini, Demetrio, Fattoretti, Patrizia, Conti, Fiorenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292745/ https://www.ncbi.nlm.nih.gov/pubmed/25590040 http://dx.doi.org/10.1002/acn3.42 |
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