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miR-141 regulates TGF-β1-induced epithelial-mesenchymal transition through repression of HIPK2 expression in renal tubular epithelial cells

Epithelial-mesenchymal transition (EMT) plays a critical role in embryonic development, wound healing, tissue regeneration, cancer progression and organ fibrosis. The proximal tubular epithelial cells undergo EMT, resulting in matrix-producing fibroblasts and thereby contribute to the pathogenesis o...

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Detalles Bibliográficos
Autores principales: HUANG, YUANHANG, TONG, JUNRONG, HE, FENG, YU, XINPEI, FAN, LIMING, HU, JING, TAN, JIANGPING, CHEN, ZHENGLIANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292766/
https://www.ncbi.nlm.nih.gov/pubmed/25421593
http://dx.doi.org/10.3892/ijmm.2014.2008