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High-fat diet decreases the expression of Kiss1 mRNA and kisspeptin in the ovary, and increases ovulatory dysfunction in postpubertal female rats

BACKGROUND: Female reproductive health is noticeably compromised by obesity. The underlying mechanisms remain to be elucidated. Accumulating evidence indicates that the expression level of ovarian Kiss1 peaks in the afternoon during prooestrus, suggesting local regulatory roles for Kiss1 in the ovul...

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Detalles Bibliográficos
Autores principales: Zhou, Qiangyong, Chen, Haiyan, Yang, Simeng, Li, Yuehua, Wang, Binqiao, Chen, Yuanyuan, Wu, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292805/
https://www.ncbi.nlm.nih.gov/pubmed/25542298
http://dx.doi.org/10.1186/1477-7827-12-127