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High-fat diet decreases the expression of Kiss1 mRNA and kisspeptin in the ovary, and increases ovulatory dysfunction in postpubertal female rats
BACKGROUND: Female reproductive health is noticeably compromised by obesity. The underlying mechanisms remain to be elucidated. Accumulating evidence indicates that the expression level of ovarian Kiss1 peaks in the afternoon during prooestrus, suggesting local regulatory roles for Kiss1 in the ovul...
Autores principales: | Zhou, Qiangyong, Chen, Haiyan, Yang, Simeng, Li, Yuehua, Wang, Binqiao, Chen, Yuanyuan, Wu, Xueqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292805/ https://www.ncbi.nlm.nih.gov/pubmed/25542298 http://dx.doi.org/10.1186/1477-7827-12-127 |
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