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Assessment of patient-derived tumour xenografts (PDXs) as a discovery tool for cancer epigenomics

BACKGROUND: The use of tumour xenografts is a well-established research tool in cancer genomics but has not yet been comprehensively evaluated for cancer epigenomics. METHODS: In this study, we assessed the suitability of patient-derived tumour xenografts (PDXs) for methylome analysis using Infinium...

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Detalles Bibliográficos
Autores principales:	Guilhamon, Paul, Butcher, Lee M, Presneau, Nadege, Wilson, Gareth A, Feber, Andrew, Paul, Dirk S, Schütte, Moritz, Haybaeck, Johannes, Keilholz, Ulrich, Hoffman, Jens, Ross, Mark T, Flanagan, Adrienne M, Beck, Stephan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292812/ https://www.ncbi.nlm.nih.gov/pubmed/25587359 http://dx.doi.org/10.1186/s13073-014-0116-0

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