Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

INTRODUCTION: Activation of the inflammasome has been implicated in the pathology of various autoinflammatory and autoimmune diseases. While the NLRP3 inflammasome has been linked to arthritis progression, little is known about its synovial regulation or contribution to joint histopathology. Regulat...

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Detalles Bibliográficos
Autores principales: Greenhill, Claire J, Jones, Gareth W, Nowell, Mari A, Newton, Zarabeth, Harvey, Ann K, Moideen, Abdul N, Collins, Fraser L, Bloom, Anja C, Coll, Rebecca C, Robertson, Avril AB, Cooper, Matthew A, Rosas, Marcela, Taylor, Philip R, O’Neill, Luke A, Humphreys, Ian R, Williams, Anwen S, Jones, Simon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292830/
https://www.ncbi.nlm.nih.gov/pubmed/25175678
http://dx.doi.org/10.1186/s13075-014-0419-y

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