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Rapid modeling of cooperating genetic events in cancer through somatic genome editing
Cancer is a multistep process that involves mutations and other alterations in oncogenes and tumor suppressor genes(1). Genome sequencing studies have identified a large collection of genetic alterations that occur in human cancers(2–4). However, the determination of which mutations are causally rel...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292871/ https://www.ncbi.nlm.nih.gov/pubmed/25337879 http://dx.doi.org/10.1038/nature13906 |