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A rationally designed nanoparticle for RNA interference therapy in B-lineage lymphoid malignancies
The purposes of the present study were to further evaluate the biologic significance of the CD22ΔE12 molecular lesion and determine if it could serve as a molecular target for RNA interference (RNAi) therapy. We show that both pediatric and adult B-lineage lymphoid malignancies are characterized by...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292938/ https://www.ncbi.nlm.nih.gov/pubmed/25599086 http://dx.doi.org/10.1016/j.ebiom.2014.10.013 |