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Functional selectivity and time-dependence of μ-opioid receptor desensitization at nerve terminals in the mouse ventral tegmental area

BACKGROUND AND PURPOSE: The majority of studies examining desensitization of the μ-opioid receptor (MOR) have examined those located at cell bodies. However, MORs are extensively expressed at nerve terminals throughout the mammalian nervous system. This study is designed to investigate agonist-induc...

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Detalles Bibliográficos
Autores principales: Lowe, J D, Bailey, C P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292961/
https://www.ncbi.nlm.nih.gov/pubmed/24467517
http://dx.doi.org/10.1111/bph.12605