Cargando…
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling
Blood vessel stability is essential for embryonic development; in the adult, many diseases are associated with loss of vascular integrity. The ETS transcription factor ERG drives expression of VE-cadherin and controls junctional integrity. We show that constitutive endothelial deletion of ERG (Erg(c...
Autores principales: | Birdsey, Graeme M., Shah, Aarti V., Dufton, Neil, Reynolds, Louise E., Osuna Almagro, Lourdes, Yang, Youwen, Aspalter, Irene M., Khan, Samia T., Mason, Justin C., Dejana, Elisabetta, Göttgens, Berthold, Hodivala-Dilke, Kairbaan, Gerhardt, Holger, Adams, Ralf H., Randi, Anna M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292982/ https://www.ncbi.nlm.nih.gov/pubmed/25584796 http://dx.doi.org/10.1016/j.devcel.2014.11.016 |
Ejemplares similares
-
The Transcription Factor ERG Regulates Super-Enhancers Associated With an Endothelial-Specific Gene Expression Program
por: Kalna, Viktoria, et al.
Publicado: (2019) -
Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis
por: Dufton, Neil P., et al.
Publicado: (2017) -
Author Correction: Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis
por: Dufton, Neil P., et al.
Publicado: (2020) -
Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG
por: Shah, Aarti V., et al.
Publicado: (2016) -
The endothelial transcription factor ERG mediates Angiopoietin-1-dependent control of Notch signalling and vascular stability
por: Shah, A. V., et al.
Publicado: (2017)