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RAB1A promotes Vaccinia virus replication by facilitating the production of intracellular enveloped virions
Vaccinia virus (VACV) is a large double-stranded DNA virus with a complex cytoplasmic replication cycle that exploits numerous cellular proteins. This work characterises the role of a proviral cellular protein, the small GTPase RAB1A, in VACV replication. Using siRNA, we identified RAB1A as required...
Autores principales: | Pechenick Jowers, Tali, Featherstone, Rebecca J., Reynolds, Danielle K., Brown, Helen K., James, John, Prescott, Alan, Haga, Ismar R., Beard, Philippa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292983/ https://www.ncbi.nlm.nih.gov/pubmed/25462347 http://dx.doi.org/10.1016/j.virol.2014.11.007 |
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