Vasculopathy associated hyperangiotensinemia mobilizes hematopoietic stem cells/progenitors through endothelial AT(2)R and cytoskeletal dysregulation

Patients in organ failure of vascular origin have increased circulating hematopoietic stem cells and progenitors (HSC/P). Plasma levels of angiotensin II (Ang-II), are commonly increased in vasculopathies. Hyperangiotensinemia results in activation of a very distinct Ang-II receptor set, Rho-family...

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Detalles Bibliográficos
Autores principales: Chang, Kyung Hee, Nayak, Ramesh C., Roy, Swarnava, Perumbeti, Ajay, Wellendorf, Ashley M., Bezold, Katie Y., Pirman, Megan, Hill, Sarah E., Starnes, Joseph, Loberg, Anastacia, Zhou, Xuan, Inagami, Tadashi, Zheng, Yi, Malik, Punam, Cancelas, Jose A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293039/
https://www.ncbi.nlm.nih.gov/pubmed/25574809
http://dx.doi.org/10.1038/ncomms6914

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