Cargando…
On the role of the endogenous opioid system in regulating epidermal homeostasis
The presence of functional opioid receptors on epidermal keratinocytes, with attendant regulation of keratinocyte proliferation and differentiation, indicate their novel role in maintaining epidermal homeostasis. Expression of proenkephalin precursors and neuropeptide products in the same compartmen...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293046/ https://www.ncbi.nlm.nih.gov/pubmed/25573044 http://dx.doi.org/10.1038/jid.2014.458 |
| _version_ | 1782352566512779264 |
|---|---|
| author | Slominski, Andrzej |
| author_facet | Slominski, Andrzej |
| author_sort | Slominski, Andrzej |
| collection | PubMed |
| description | The presence of functional opioid receptors on epidermal keratinocytes, with attendant regulation of keratinocyte proliferation and differentiation, indicate their novel role in maintaining epidermal homeostasis. Expression of proenkephalin precursors and neuropeptide products in the same compartment opens an opportunity to study the role of this endogenous opioid circuitry, with its regulators, in modulating epidermal barrier function. |
| format | Online Article Text |
| id | pubmed-4293046 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2015 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-42930462015-08-01 On the role of the endogenous opioid system in regulating epidermal homeostasis Slominski, Andrzej J Invest Dermatol Article The presence of functional opioid receptors on epidermal keratinocytes, with attendant regulation of keratinocyte proliferation and differentiation, indicate their novel role in maintaining epidermal homeostasis. Expression of proenkephalin precursors and neuropeptide products in the same compartment opens an opportunity to study the role of this endogenous opioid circuitry, with its regulators, in modulating epidermal barrier function. 2015-02 /pmc/articles/PMC4293046/ /pubmed/25573044 http://dx.doi.org/10.1038/jid.2014.458 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
| spellingShingle | Article Slominski, Andrzej On the role of the endogenous opioid system in regulating epidermal homeostasis |
| title | On the role of the endogenous opioid system in regulating epidermal
homeostasis |
| title_full | On the role of the endogenous opioid system in regulating epidermal
homeostasis |
| title_fullStr | On the role of the endogenous opioid system in regulating epidermal
homeostasis |
| title_full_unstemmed | On the role of the endogenous opioid system in regulating epidermal
homeostasis |
| title_short | On the role of the endogenous opioid system in regulating epidermal
homeostasis |
| title_sort | on the role of the endogenous opioid system in regulating epidermal
homeostasis |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293046/ https://www.ncbi.nlm.nih.gov/pubmed/25573044 http://dx.doi.org/10.1038/jid.2014.458 |
| work_keys_str_mv | AT slominskiandrzej ontheroleoftheendogenousopioidsysteminregulatingepidermalhomeostasis |