HTLV-1-infected CD4+ T-cells display alternative exon usages that culminate in adult T-cell leukemia

BACKGROUND: Reprogramming cellular gene transcription sustains HTLV-1 viral persistence that ultimately leads to the development of adult T-cell leukemia/lymphoma (ATLL). We hypothesized that besides these quantitative transcriptional effects, HTLV-1 qualitatively modifies the pattern of cellular ge...

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Detalles Bibliográficos
Autores principales: Thénoz, Morgan, Vernin, Céline, Mortada, Hussein, Karam, Maroun, Pinatel, Christiane, Gessain, Antoine, Webb, Thomas R, Auboeuf, Didier, Wattel, Eric, Mortreux, Franck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293115/
https://www.ncbi.nlm.nih.gov/pubmed/25519886
http://dx.doi.org/10.1186/s12977-014-0119-3

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