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Analysis of glioblastoma tumor coverage by oncolytic virus-loaded neural stem cells using MRI-based tracking and histological reconstruction

In preclinical studies, neural stem cell (NSC)-based delivery of oncolytic virus has shown great promise in the treatment of malignant glioma. Ensuring the success of this therapy will require critical evaluation of the spatial distribution of virus after NSC transplantation. In this study, the pati...

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Detalles Bibliográficos
Autores principales: Morshed, Ramin A., Gutova, Margarita, Juliano, Joseph, Barish, Michael E., Hawkins-Daarud, Andrea, Oganesyan, Diana, Vazgen, Khankaldyyan, Yang, Tang, Annala, Alexander, Ahmed, Atique U., Aboody, Karen S., Swanson, Kristin R., Moats, Rex A., Lesniak, Maciej S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293243/
https://www.ncbi.nlm.nih.gov/pubmed/25525033
http://dx.doi.org/10.1038/cgt.2014.72