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Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population

INTRODUCTION: Leukoplakia is the most common potentially malignant condition of the oral cavity. AIM: Epidemiological and clinical analysis of patients with oral leukoplakia (OL) diagnosed and treated in the Department of Maxillofacial and Oral Surgery, Medical University of Gdansk. MATERIAL AND MET...

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Autores principales: Starzyńska, Anna, Pawłowska, Anita, Renkielska, Dorota, Michajłowski, Igor, Sobjanek, Michał, Błażewicz, Izabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293380/
https://www.ncbi.nlm.nih.gov/pubmed/25610347
http://dx.doi.org/10.5114/pdia.2014.40932
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author Starzyńska, Anna
Pawłowska, Anita
Renkielska, Dorota
Michajłowski, Igor
Sobjanek, Michał
Błażewicz, Izabela
author_facet Starzyńska, Anna
Pawłowska, Anita
Renkielska, Dorota
Michajłowski, Igor
Sobjanek, Michał
Błażewicz, Izabela
author_sort Starzyńska, Anna
collection PubMed
description INTRODUCTION: Leukoplakia is the most common potentially malignant condition of the oral cavity. AIM: Epidemiological and clinical analysis of patients with oral leukoplakia (OL) diagnosed and treated in the Department of Maxillofacial and Oral Surgery, Medical University of Gdansk. MATERIAL AND METHODS: The study was retrospective and prospective. Among 55 911 patients diagnosed and treated in the Department in 1999–2009, 204 people with OL were selected. The material includes 104 women and 100 men with an average age of 58.1. Most of the patients were in the age group of 50–70 years, average age was 58.1. RESULTS: The most common concomitant disease was diabetes. More than 88% of the patients declared occurrence of OL predisposing development factors (50.49% – cigarette smoking). Three hundred and twenty foci of OL were found among patients. Homogeneous OL dominated (72.05%). Multifocal OL was diagnosed in 58.3% of patients. The most common location of lesions was buccal mucosa (52.2%). Cancers developed on the basis of OL in 7 patients (3.43%). The percentage of malignant transformation was 12.19% for untreated patients and 1.41% for treated patients. The floor of the oral cavity was proven to be the location of the highest risk of oral squamous cell carcinoma. Patients with diabetes may be more likely to develop OL. The risk of malignant transformation is relatively high. In our material it was equal to 3.43%. CONCLUSIONS: Cigarette smoking is the most important factor, which can influence the effectiveness of treatment.
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spelling pubmed-42933802015-01-21 Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population Starzyńska, Anna Pawłowska, Anita Renkielska, Dorota Michajłowski, Igor Sobjanek, Michał Błażewicz, Izabela Postepy Dermatol Alergol Original Paper INTRODUCTION: Leukoplakia is the most common potentially malignant condition of the oral cavity. AIM: Epidemiological and clinical analysis of patients with oral leukoplakia (OL) diagnosed and treated in the Department of Maxillofacial and Oral Surgery, Medical University of Gdansk. MATERIAL AND METHODS: The study was retrospective and prospective. Among 55 911 patients diagnosed and treated in the Department in 1999–2009, 204 people with OL were selected. The material includes 104 women and 100 men with an average age of 58.1. Most of the patients were in the age group of 50–70 years, average age was 58.1. RESULTS: The most common concomitant disease was diabetes. More than 88% of the patients declared occurrence of OL predisposing development factors (50.49% – cigarette smoking). Three hundred and twenty foci of OL were found among patients. Homogeneous OL dominated (72.05%). Multifocal OL was diagnosed in 58.3% of patients. The most common location of lesions was buccal mucosa (52.2%). Cancers developed on the basis of OL in 7 patients (3.43%). The percentage of malignant transformation was 12.19% for untreated patients and 1.41% for treated patients. The floor of the oral cavity was proven to be the location of the highest risk of oral squamous cell carcinoma. Patients with diabetes may be more likely to develop OL. The risk of malignant transformation is relatively high. In our material it was equal to 3.43%. CONCLUSIONS: Cigarette smoking is the most important factor, which can influence the effectiveness of treatment. Termedia Publishing House 2014-12-03 2014-12 /pmc/articles/PMC4293380/ /pubmed/25610347 http://dx.doi.org/10.5114/pdia.2014.40932 Text en Copyright © 2014 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Starzyńska, Anna
Pawłowska, Anita
Renkielska, Dorota
Michajłowski, Igor
Sobjanek, Michał
Błażewicz, Izabela
Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population
title Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population
title_full Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population
title_fullStr Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population
title_full_unstemmed Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population
title_short Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population
title_sort oral premalignant lesions: epidemiological and clinical analysis in the northern polish population
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293380/
https://www.ncbi.nlm.nih.gov/pubmed/25610347
http://dx.doi.org/10.5114/pdia.2014.40932
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