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Dermoscopic and clinical features of trunk melanomas

INTRODUCTION: Malignant melanomas account for 5% of all skin cancers and usually have a fatal clinical course. Additionally, the incidence of melanoma increases more rapidly than in any other cancer, and this has been attributed to the development of highly sensitive diagnostic techniques, mainly de...

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Autores principales: Emiroglu, Nazan, Pelin Cengiz, Fatma, Hofmann-Wellenhof, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293392/
https://www.ncbi.nlm.nih.gov/pubmed/25610350
http://dx.doi.org/10.5114/pdia.2014.47119
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author Emiroglu, Nazan
Pelin Cengiz, Fatma
Hofmann-Wellenhof, Rainer
author_facet Emiroglu, Nazan
Pelin Cengiz, Fatma
Hofmann-Wellenhof, Rainer
author_sort Emiroglu, Nazan
collection PubMed
description INTRODUCTION: Malignant melanomas account for 5% of all skin cancers and usually have a fatal clinical course. Additionally, the incidence of melanoma increases more rapidly than in any other cancer, and this has been attributed to the development of highly sensitive diagnostic techniques, mainly dermoscopy, which allows for early diagnosis. The phenotypic manifestations of gene/environment interactions, environmental factor and genetic factors may determine subtypes and anatomic localization of melanoma. Histopathologic subtypes, risk factors, and thickness of the skin are different in trunk melanomas. AIM: To determine the frequency of dermatoscopic features in trunk melanomas. This study also investigates dermoscopic features according to the diameter of lesions. MATERIAL AND METHODS: Seventy-one trunk melanomas were included. Their dermoscopic and clinical images, histopathological and clinical data were assessed. The relations between the diameter, Breslow thickness and dermoscopic characteristics were evaluated. RESULTS: The most common dermoscopic findings of trunk melanomas were the multicomponent pattern (55 patients, 77.5%), asymmetry (62 patients; 87.3%), blue-gray veil (59 patients, 83.1%), and color variety (56 patients, 78.8%). When dermoscopic findings were compared, a multicomponent pattern (p = 0.03), milky-red areas (p = 0.001), blue-gray veils (p = 0.023), and regression structures (p = 0.037) were more common in large melanomas than in small melanomas. CONCLUSIONS: The most common dermoscopic findings of trunk melanomas were the multicomponent pattern, asymmetry and blue-gray veil, color variety. The multicomponent pattern, milky-red areas, blue-gray veils, regression structures were statistically significant dermoscopic features in a group of large-diameter melanomas, compared to small melanomas.
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spelling pubmed-42933922015-01-21 Dermoscopic and clinical features of trunk melanomas Emiroglu, Nazan Pelin Cengiz, Fatma Hofmann-Wellenhof, Rainer Postepy Dermatol Alergol Original Paper INTRODUCTION: Malignant melanomas account for 5% of all skin cancers and usually have a fatal clinical course. Additionally, the incidence of melanoma increases more rapidly than in any other cancer, and this has been attributed to the development of highly sensitive diagnostic techniques, mainly dermoscopy, which allows for early diagnosis. The phenotypic manifestations of gene/environment interactions, environmental factor and genetic factors may determine subtypes and anatomic localization of melanoma. Histopathologic subtypes, risk factors, and thickness of the skin are different in trunk melanomas. AIM: To determine the frequency of dermatoscopic features in trunk melanomas. This study also investigates dermoscopic features according to the diameter of lesions. MATERIAL AND METHODS: Seventy-one trunk melanomas were included. Their dermoscopic and clinical images, histopathological and clinical data were assessed. The relations between the diameter, Breslow thickness and dermoscopic characteristics were evaluated. RESULTS: The most common dermoscopic findings of trunk melanomas were the multicomponent pattern (55 patients, 77.5%), asymmetry (62 patients; 87.3%), blue-gray veil (59 patients, 83.1%), and color variety (56 patients, 78.8%). When dermoscopic findings were compared, a multicomponent pattern (p = 0.03), milky-red areas (p = 0.001), blue-gray veils (p = 0.023), and regression structures (p = 0.037) were more common in large melanomas than in small melanomas. CONCLUSIONS: The most common dermoscopic findings of trunk melanomas were the multicomponent pattern, asymmetry and blue-gray veil, color variety. The multicomponent pattern, milky-red areas, blue-gray veils, regression structures were statistically significant dermoscopic features in a group of large-diameter melanomas, compared to small melanomas. Termedia Publishing House 2014-12-03 2014-12 /pmc/articles/PMC4293392/ /pubmed/25610350 http://dx.doi.org/10.5114/pdia.2014.47119 Text en Copyright © 2014 Termedia http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License, permitting all non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Paper
Emiroglu, Nazan
Pelin Cengiz, Fatma
Hofmann-Wellenhof, Rainer
Dermoscopic and clinical features of trunk melanomas
title Dermoscopic and clinical features of trunk melanomas
title_full Dermoscopic and clinical features of trunk melanomas
title_fullStr Dermoscopic and clinical features of trunk melanomas
title_full_unstemmed Dermoscopic and clinical features of trunk melanomas
title_short Dermoscopic and clinical features of trunk melanomas
title_sort dermoscopic and clinical features of trunk melanomas
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293392/
https://www.ncbi.nlm.nih.gov/pubmed/25610350
http://dx.doi.org/10.5114/pdia.2014.47119
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