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Cerebellar Directed Optogenetic Intervention Inhibits Spontaneous Hippocampal Seizures in a Mouse Model of Temporal Lobe Epilepsy1 2
Temporal lobe epilepsy is often medically refractory and new targets for intervention are needed. We used a mouse model of temporal lobe epilepsy, on-line seizure detection, and responsive optogenetic intervention to investigate the potential for cerebellar control of spontaneous temporal lobe seizu...
Autores principales: | Krook-Magnuson, Esther, Szabo, Gergely G., Armstrong, Caren, Oijala, Mikko, Soltesz, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293636/ https://www.ncbi.nlm.nih.gov/pubmed/25599088 http://dx.doi.org/10.1523/ENEURO.0005-14.2014 |
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