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P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review
Resistance of solid tumors to treatment is significantly attributed to pharmacokinetic reasons at both cellular and multi-cellular levels. Anticancer agent must be bio-available at the site of action in a cytotoxic concentration to exert its proposed activity. P-glycoprotein (P-gp) is a member of th...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293676/ https://www.ncbi.nlm.nih.gov/pubmed/25685543 http://dx.doi.org/10.1016/j.jare.2014.11.008 |