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P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review

Resistance of solid tumors to treatment is significantly attributed to pharmacokinetic reasons at both cellular and multi-cellular levels. Anticancer agent must be bio-available at the site of action in a cytotoxic concentration to exert its proposed activity. P-glycoprotein (P-gp) is a member of th...

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Detalles Bibliográficos
Autores principales: Abdallah, Hossam M., Al-Abd, Ahmed M., El-Dine, Riham Salah, El-Halawany, Ali M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293676/
https://www.ncbi.nlm.nih.gov/pubmed/25685543
http://dx.doi.org/10.1016/j.jare.2014.11.008