Design, Synthesis and Evaluation of New 2, 6-Dihydroimidazo[1, 2-c]Pyrimido[5, 4-e]-Pyrimidine-5(3H)-thiones as Possible Antihistaminic/Antiasthmatic Agents§

A series of new 10-(alkylamino)-8-methyl-2, 6-dihydroimidazo[1, 2-c]pyrimido[5, 4-e]pyrimidine-5(3H)-thiones (4a-g) were subjected to molecular property prediction (drug-likeness, lipophilicity and solubility parameters) using Osiris Property Explorer, ALOGPS 2.1, Molinspiration and ACD/Chemsketch 1...

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Detalles Bibliográficos
Autores principales: Sirisha, K., Achaiah, G., Ram Rao, A. Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293683/
https://www.ncbi.nlm.nih.gov/pubmed/25593385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293683/
https://www.ncbi.nlm.nih.gov/pubmed/25593385

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