Cargando…

Direct Sequencing of Cyclooxygenase-2 (COX-2) Revealed an Intronic Variant rs201231411 in Iranian Patients with Pancreatic Cancer

BACKGROUND There are hoarding documents for the biological importance of cyclooxygenase-2 (COX-2) in pancreatic carcinogenesis. We aimed to thoroughly investigate the DNA sequence variations of whole COX-2 exons in a large case-control study of pancreatic cancer by direct sequencing. METHODS The ent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mohamadkhani, Ashraf, Akbari, Mohammad Reza, Ghanbari, Reza, Naderi, Elnaz, Rezanejad-Asl, Parisa, Pourshams, Akram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Iranian Association of Gastroerterology and Hepatology 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293795/ https://www.ncbi.nlm.nih.gov/pubmed/25628848

Ejemplares similares

Detection of TP53 R249 Mutation in Iranian Patients with Pancreatic Cancer
por: Mohamadkhani, Ashraf, et al.
Publicado: (2013)

Inverse Association of Plasma Level of Glutathione Peroxidase with Liver Fibrosis in Chronic Hepatitis B: Potential Role of Iron
por: Moossavi, Shirin, et al.
Publicado: (2016)

Network of microRNAs-mRNAs Interactions in Pancreatic Cancer
por: Naderi, Elnaz, et al.
Publicado: (2014)

Expression of cyclooxygenase-2 (COX-2) in pituitary tumours
por: Sokołowski, Grzegorz, et al.
Publicado: (2012)

Identification of a Novel Stop Loss Mutation in P2RX2 Gene in an Iranian Family with Autosomal Nonsyndromic Hearing Loss
por: Azizi Malamiri, Reza, et al.
Publicado: (2021)

Dehydroepiandrosterone modulates oxidative DNA damage in pancreatic cancer: A case–control study
por: Fazli, Hamid Reza, et al.
Publicado: (2021)

Cyclooxygenase (COX) Inhibitors and the Newborn Kidney
por: Smith, Francine G., et al.
Publicado: (2012)

Colorectal Carcinoma, Cyclooxygenases, and COX Inhibitors
por: Ganduri, Vinutna, et al.
Publicado: (2022)

Pancreatic Stellate Cells (PSCs) express Cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs
por: Yoshida, Seiya, et al.
Publicado: (2005)

The Possible Role of TLR2 in Chronic Hepatitis B Patients with Precore Mutation
por: Moradzadeh, Malihe, et al.
Publicado: (2013)

Cox-2: Where are we in 2003? - The role of cyclooxygenase-2 in bone repair
por: Einhorn, Thomas A
Publicado: (2003)

Reduction in cancer risk by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors
por: Harris, Randall E, et al.
Publicado: (2012)

Cyclooxygenase-2 (COX-2) inhibitors: future therapeutic strategies for epilepsy management
por: Rawat, Chitra, et al.
Publicado: (2019)

Bioactivity of dihydropyrimidinone derivatives as inhibitors of cyclooxygenase-2 (COX-2): an in silico approach
por: Haq, Kautsar Ul, et al.
Publicado: (2023)

Nucleobindin Co-Localizes and Associates with Cyclooxygenase (COX)-2 in Human Neutrophils
por: Leclerc, Patrick, et al.
Publicado: (2008)

Cyclooxygenase in normal human tissues – is COX-1 really a constitutive isoform, and COX-2 an inducible isoform?
por: Zidar, Nina, et al.
Publicado: (2009)

Diagnostic Significance of Serum Fatty Acid Synthase in Patients with Pancreatic Cancer
por: Fazli, Hamid Reza, et al.
Publicado: (2021)

Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors
por: Harris, Randall E, et al.
Publicado: (2006)

Regional Differences in the Neuronal Expression of Cyclooxygenase-2 (COX-2) in the Newborn Pig Brain
por: Oláh, Orsolya, et al.
Publicado: (2012)

Reversible Suppression of Cyclooxygenase 2 (COX-2) Expression In Vivo by Inducible RNA Interference
por: Zaiss, Anne K., et al.
Publicado: (2014)

Transgenic expression of cyclooxygenase-2 (COX2) causes premature aging phenotypes in mice
por: Kim, Joohwee, et al.
Publicado: (2016)

Neurobiology and Therapeutic Potential of Cyclooxygenase-2 (COX-2) Inhibitors for Inflammation in Neuropsychiatric Disorders
por: Sethi, Rickinder, et al.
Publicado: (2019)

The Search for Cyclooxygenase-2 (COX-2) Inhibitors for the Treatment of Inflammation Disease: An in-silico Study
por: Ruslin, Ruslin, et al.
Publicado: (2022)

Binding Energy Calculation of Patchouli Alcohol Isomer Cyclooxygenase Complexes Suggested as COX-1/COX-2 Selective Inhibitor
por: Raharjo, Sentot Joko, et al.
Publicado: (2014)

Obesity and hypertension in an Iranian cohort study; Iranian women experience higher rates of obesity and hypertension than American women
por: Bahrami, Hossein, et al.
Publicado: (2006)

An Increased Level of Aryl Hydrocarbon Receptor in Patients with Pancreatic Cancer
por: Masoudi, Sahar, et al.
Publicado: (2019)

Polymorphisms in prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) and risk of colorectal cancer
por: Cox, D G, et al.
Publicado: (2004)

Expression of cyclooxygenase-2 (COX-2) in tumour and stroma compartments in cervical cancer: clinical implications
por: Ferrandina, G, et al.
Publicado: (2002)

Prognostic significance of cyclooxygenase-2 (COX-2) expression in patients with surgically resectable adenocarcinoma of the oesophagus
por: Bhandari, Pradeep, et al.
Publicado: (2006)

PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model
por: Tietz, Ole, et al.
Publicado: (2016)

Commentary: Neurobiology and Therapeutic Potential of Cyclooxygenase-2 (COX-2) Inhibitors for Inflammation in Neuropsychiatric Disorders
por: Westwell-Roper, Clara, et al.
Publicado: (2020)

In-vitro and computational analysis of Urolithin-A for anti-inflammatory activity on Cyclooxygenase 2 (COX-2)
por: Revankar, Archana G., et al.
Publicado: (2023)

Assessing the Relationship between Chronic Lymphoid Leukemia Mortality Rates and Human Development Index: A 26-Year Trend Analysis Using Location-Scale Mixed Effects Model
por: REZANEJAD ASL, Parisa, et al.
Publicado: (2021)

Association of intron and exon polymorphisms of p53 gene in Iranian patients with gastritis
por: Najjar Sadeghi, Rouhallah, et al.
Publicado: (2013)

Acyl chain-dependent effect of lysophosphatidylcholine on cyclooxygenase (COX)-2 expression in endothelial cells
por: Brkić, Lada, et al.
Publicado: (2012)

Risk of Cardiovascular Events and Cyclooxygenase-2 Inhibitors
por: Tabrizchi, Reza
Publicado: (2006)

The Impact of Illicit Drug Use on Spontaneous Hepatitis C Clearance: Experience from a Large Cohort Population Study
por: Poustchi, Hossein, et al.
Publicado: (2011)

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney
por: Pelligand, L., et al.
Publicado: (2015)

The Influence of Glycosylation of Natural and Synthetic Prenylated Flavonoids on Binding to Human Serum Albumin and Inhibition of Cyclooxygenases COX-1 and COX-2
por: Tronina, Tomasz, et al.
Publicado: (2017)

Cyclooxygenase-2 (COX-2) as a Target of Anticancer Agents: A Review of Novel Synthesized Scaffolds Having Anticancer and COX-2 Inhibitory Potentialities
por: Mohsin, Noor ul Amin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0cltlb64qf41og28iso923l85b