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Genetic association between germline JAK2 polymorphisms and myeloproliferative neoplasms in Hong Kong Chinese population: a case–control study

BACKGROUND: Myeloproliferative neoplasms (MPNs) are a group of haematological malignancies that can be characterised by a somatic mutation (JAK2V617F). This mutation causes the bone marrow to produce excessive blood cells and is found in polycythaemia vera (~95%), essential thrombocythaemia and prim...

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Detalles Bibliográficos
Autores principales: Koh, Su Pin, Yip, Shea Ping, Lee, Kwok Kuen, Chan, Chi Chung, Lau, Sze Man, Kho, Chi Shan, Lau, Chi Kuen, Lin, Shek Ying, Lau, Yat Ming, Wong, Lap Gate, Au, Ka Leung, Wong, Kit Fai, Chu, Raymond W, Yu, Pui Hung, Chow, Eudora YD, Leung, Kate FS, Tsoi, Wai Chiu, Yung, Benjamin YM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293821/
https://www.ncbi.nlm.nih.gov/pubmed/25526816
http://dx.doi.org/10.1186/s12863-014-0147-y