The genetics of Ménière’s disease

Our understanding of the genetic basis of Ménière’s disease (MD) is still limited. Although the familial clustering and the geographical and racial differences in incidence strongly suggest a certain role for genetic factors in the development of MD, no convincing evidence for an association with an...

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Detalles Bibliográficos
Autores principales: Chiarella, Giuseppe, Petrolo, C, Cassandro, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293923/
https://www.ncbi.nlm.nih.gov/pubmed/25609993
http://dx.doi.org/10.2147/TACG.S59024
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author Chiarella, Giuseppe
Petrolo, C
Cassandro, E
author_facet Chiarella, Giuseppe
Petrolo, C
Cassandro, E
author_sort Chiarella, Giuseppe
collection PubMed
description Our understanding of the genetic basis of Ménière’s disease (MD) is still limited. Although the familial clustering and the geographical and racial differences in incidence strongly suggest a certain role for genetic factors in the development of MD, no convincing evidence for an association with any gene exists, at present. In this review, starting from rational bases for a genetic approach to MD, we explored the numerous reports published in literature and summarize the recent advances in understanding of the genetic fundaments of the disease.
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spelling pubmed-42939232015-01-21 The genetics of Ménière’s disease Chiarella, Giuseppe Petrolo, C Cassandro, E Appl Clin Genet Review Our understanding of the genetic basis of Ménière’s disease (MD) is still limited. Although the familial clustering and the geographical and racial differences in incidence strongly suggest a certain role for genetic factors in the development of MD, no convincing evidence for an association with any gene exists, at present. In this review, starting from rational bases for a genetic approach to MD, we explored the numerous reports published in literature and summarize the recent advances in understanding of the genetic fundaments of the disease. Dove Medical Press 2015-01-08 /pmc/articles/PMC4293923/ /pubmed/25609993 http://dx.doi.org/10.2147/TACG.S59024 Text en © 2015 Chiarella et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Chiarella, Giuseppe
Petrolo, C
Cassandro, E
The genetics of Ménière’s disease
title The genetics of Ménière’s disease
title_full The genetics of Ménière’s disease
title_fullStr The genetics of Ménière’s disease
title_full_unstemmed The genetics of Ménière’s disease
title_short The genetics of Ménière’s disease
title_sort genetics of ménière’s disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293923/
https://www.ncbi.nlm.nih.gov/pubmed/25609993
http://dx.doi.org/10.2147/TACG.S59024
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