Recombinant adeno-associated virus serotype 9 with p65 ribozyme protects H9c2 cells from oxidative stress through inhibiting NF-κB signaling pathway

BACKGROUND: Oxidative stress is a major mechanism underlying the pathogenesis of cardiovascular disease. It can trigger inflammatory cascades which are primarily mediated via nuclear factor-κB (NF-κB). The NF-κB transcription factor family includes several subunits (p50, p52, p65, c-Rel, and Rel B)...

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Detalles Bibliográficos
Autores principales: SUN, Zhan, MA, Yi-Tong, CHEN, Bang-Dang, LIU, Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294148/
https://www.ncbi.nlm.nih.gov/pubmed/25593580
http://dx.doi.org/10.11909/j.issn.1671-5411.2014.04.006

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