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Cognitive impairment in heart failure patients
Cognitive damage in heart failure (HF) involves different domains thus interfering with the ability for single patient to self-care and to cope with treatment regimens, modifying symptoms and health behaviours. Many cerebral and functional changes were detected in brain imaging, involving areas of b...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294149/ https://www.ncbi.nlm.nih.gov/pubmed/25593581 http://dx.doi.org/10.11909/j.issn.1671-5411.2014.04.007 |
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author | Leto, Laura Feola, Mauro |
author_facet | Leto, Laura Feola, Mauro |
author_sort | Leto, Laura |
collection | PubMed |
description | Cognitive damage in heart failure (HF) involves different domains thus interfering with the ability for single patient to self-care and to cope with treatment regimens, modifying symptoms and health behaviours. Many cerebral and functional changes were detected in brain imaging, involving areas of both grey and white matter deputed to cognition. Although various instruments are available to explore cognition, no consensus was obtained on better tools to be used in HF population. Reduction in cerebral blood flow, decreased cardiac output, alterations of cerebrovascular reactivity and modification of blood pressure levels are the main features involved in the etiopathogenetic mechanisms of cognitive deficit. Several cardiac variables, laboratory parameters, demographic and clinical elements were studied for their possible relation with cognition and should be properly evaluated to define patients at increased risk of impairment. The present review gathers available data pointing out assured information and discussing possible areas of research development. |
format | Online Article Text |
id | pubmed-4294149 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Science Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-42941492015-01-20 Cognitive impairment in heart failure patients Leto, Laura Feola, Mauro J Geriatr Cardiol Review Cognitive damage in heart failure (HF) involves different domains thus interfering with the ability for single patient to self-care and to cope with treatment regimens, modifying symptoms and health behaviours. Many cerebral and functional changes were detected in brain imaging, involving areas of both grey and white matter deputed to cognition. Although various instruments are available to explore cognition, no consensus was obtained on better tools to be used in HF population. Reduction in cerebral blood flow, decreased cardiac output, alterations of cerebrovascular reactivity and modification of blood pressure levels are the main features involved in the etiopathogenetic mechanisms of cognitive deficit. Several cardiac variables, laboratory parameters, demographic and clinical elements were studied for their possible relation with cognition and should be properly evaluated to define patients at increased risk of impairment. The present review gathers available data pointing out assured information and discussing possible areas of research development. Science Press 2014-12 /pmc/articles/PMC4294149/ /pubmed/25593581 http://dx.doi.org/10.11909/j.issn.1671-5411.2014.04.007 Text en Institute of Geriatric Cardiology http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission. |
spellingShingle | Review Leto, Laura Feola, Mauro Cognitive impairment in heart failure patients |
title | Cognitive impairment in heart failure patients |
title_full | Cognitive impairment in heart failure patients |
title_fullStr | Cognitive impairment in heart failure patients |
title_full_unstemmed | Cognitive impairment in heart failure patients |
title_short | Cognitive impairment in heart failure patients |
title_sort | cognitive impairment in heart failure patients |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294149/ https://www.ncbi.nlm.nih.gov/pubmed/25593581 http://dx.doi.org/10.11909/j.issn.1671-5411.2014.04.007 |
work_keys_str_mv | AT letolaura cognitiveimpairmentinheartfailurepatients AT feolamauro cognitiveimpairmentinheartfailurepatients |