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Senescence of tumor cells induced by oxaliplatin increases the efficiency of a lipid A immunotherapy via the recruitment of neutrophils

Management of advanced colorectal cancer is challenging due to the lack of efficient therapy. The lipid A, OM-174 exhibited antitumor activity in colorectal cancer. We explored the anticancer efficacy of this compound in rats bearing large colorectal tumors in combination with the platinum derivativ...

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Detalles Bibliográficos
Autores principales: Seignez, Cédric, Martin, Amandine, Rollet, Claire-Emmanuelle, Racoeur, Cindy, Scagliarini, Alessandra, Jeannin, Jean-François, Bettaieb, Ali, Paul, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294335/
https://www.ncbi.nlm.nih.gov/pubmed/25347345

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