Cargando…

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue

An understanding of tissue data variability in relation to processing techniques during and postsurgery would be desirable when testing surgical specimens for clinical diagnostics, drug development, or identification of predictive biomarkers. Specimens of normal and colorectal cancer (CRC) tissues r...

Descripción completa

Detalles Bibliográficos
Autores principales:	David, Kerstin A., Unger, Florian T., Uhlig, Philipp, Juhl, Hartmut, Moore, Helen M., Compton, Carolyn, Nashan, Björn, Dörner, Arnulf, de Weerth, Andreas, Zornig, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294341/ https://www.ncbi.nlm.nih.gov/pubmed/25526028

Ejemplares similares

Nanoproteomic analysis of ischemia-dependent changes in signaling protein phosphorylation in colorectal normal and cancer tissue
por: Unger, Florian T., et al.
Publicado: (2016)

Regulation of brown adipose tissue recruitment, metabolism and thermogenic function by peroxisome proliferator-activated receptor γ
por: Bolsoni-Lopes, Andressa, et al.
Publicado: (2015)

Identification and Validation of a Potential Marker of Tissue Quality Using Gene Expression Analysis of Human Colorectal Tissue
por: Lange, Nicole, et al.
Publicado: (2015)

Checkpoint Blockade–Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines
por: Reschke, Robin, et al.
Publicado: (2022)

Comparison of SARS-CoV-2 RT-PCR on a high-throughput molecular diagnostic platform and the cobas SARS-CoV-2 test for the diagnostic of COVID-19 on various clinical samples
por: Opota, Onya, et al.
Publicado: (2020)

Survey of senescent cell markers with age in human tissues
por: Idda, M. Laura, et al.
Publicado: (2020)

Intermittent high-dose treatment with erlotinib enhances therapeutic efficacy in EGFR-mutant lung cancer
por: Schöttle, Jakob, et al.
Publicado: (2015)

Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas
por: Li, Jie, et al.
Publicado: (2014)

Lymphatic Tissue Bioengineering for the Treatment of Postsurgical Lymphedema
por: Sung, Cynthia J., et al.
Publicado: (2022)

EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models
por: Venugopalan, Abhilash, et al.
Publicado: (2016)

Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin
por: Mehdipour, Melod, et al.
Publicado: (2020)

Tissue- and age-dependent expression of RNA-binding proteins that influence mRNA turnover and translation
por: Masuda, Kiyoshi, et al.
Publicado: (2009)

Muscle-dependent regulation of adipose tissue function in long-lived growth hormone-mutant mice
por: Li, Xinna, et al.
Publicado: (2020)

AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer
por: Jhaveri, Teraneh Z., et al.
Publicado: (2015)

Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status
por: Soares, Maria, et al.
Publicado: (2016)

Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition
por: Shen, Ying, et al.
Publicado: (2015)

Influence of tumor microenvironment on prognosis in colorectal cancer: Tissue architecture-dependent signature of endosialin (TEM-1) and associated proteins
por: O'Shannessy, Daniel J., et al.
Publicado: (2014)

An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival
por: Snijders, Antoine M., et al.
Publicado: (2014)

BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations
por: Deihimi, Safoora, et al.
Publicado: (2017)

Application of 3D tumoroid systems to define immune and cytotoxic therapeutic responses based on tumoroid and tissue slice culture molecular signatures
por: Finnberg, Niklas K., et al.
Publicado: (2017)

Screening of cancer tissue arrays identifies CXCR4 on adrenocortical carcinoma: correlates with expression and quantification on metastases using (64)Cu-plerixafor PET
por: Weiss, Ido D., et al.
Publicado: (2017)

Normal tissue and tumor microenvironment adaptations to aerobic exercise enhance doxorubicin anti-tumor efficacy and ameliorate its cardiotoxicity in retired breeder mice
por: Wakefield, Zachary R., et al.
Publicado: (2021)

Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming
por: Thiagarajan, Praveena S., et al.
Publicado: (2016)

Subclone Eradication Analysis Identifies Targets for Enhanced Cancer Therapy and Reveals L1 Retrotransposition as a Dynamic Source of Cancer Heterogeneity
por: Ketola, Kirsi, et al.
Publicado: (2021)

The stem cell/cancer stem cell marker ALDH1A3 regulates the expression of the survival factor tissue transglutaminase, in mesenchymal glioma stem cells
por: Sullivan, Kelly E., et al.
Publicado: (2017)

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models
por: Wong, Oi Kwan, et al.
Publicado: (2018)

Hypophosphatemia Due to Increased Effector Cell Metabolic Activity Is Associated with Neurotoxicity Symptoms in CD19-Targeted CAR T-cell Therapy
por: Tang, Jack Pengfei, et al.
Publicado: (2022)

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma
por: Li, Jie, et al.
Publicado: (2014)

Rare Presentation of Postsurgical Pyoderma Gangrenosum Presenting as Necrotizing Soft Tissue Infection
por: Flynn, Rod L., et al.
Publicado: (2019)

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors
por: Liu, Qinghai, et al.
Publicado: (2009)

Peripheral Inflammation is Associated with Altered Substantia Nigra Activity and Psychomotor Slowing in Humans
por: Brydon, Lena, et al.
Publicado: (2008)

Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge
por: Neufeld-Cohen, Adi, et al.
Publicado: (2012)

Hostility and Cellular Aging in Men from the Whitehall II Cohort
por: Brydon, Lena, et al.
Publicado: (2012)

Regulation of Bim in Health and Disease
por: Sionov, Ronit Vogt, et al.
Publicado: (2015)

Urinary thrombomodulin and catecholamine levels are interrelated in healthy volunteers immersed in cold and warm water
por: Pakanen, Lasse, et al.
Publicado: (2015)

Arterio-venous anastomoses in the human skin and their role in temperature control
por: Walløe, Lars
Publicado: (2015)

High intensity interval training in the heat enhances exercise-induced lipid peroxidation, but prevents protein oxidation in physically active men
por: Souza-Silva, Ana Angélica, et al.
Publicado: (2015)

Human whole body cold adaptation
por: Daanen, Hein A.M., et al.
Publicado: (2016)

Current understanding on the neurophysiology of behavioral thermoregulation
por: Almeida, Maria Camila, et al.
Publicado: (2015)

Insights into the role of heat shock protein 72 to whole-body heat acclimation in humans
por: Amorim, Fabiano Trigueiro, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ppsps0ta1reffp4ucf9eq8lgge