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A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours
BACKGROUND: To examine the angiopoietin pathway inhibitor trebananib IV plus the anti-VEGF agents bevacizumab or motesanib in advanced solid tumours. METHODS: In this open-label phase 1b study, patients received IV trebananib 3 mg kg(−1) QW plus bevacizumab 15 mg kg(−1) Q3W (cohort 1) or motesanib o...
Autores principales: | Hong, David S., Kurzrock, Razelle, Mulay, Marilyn, Rasmussen, Erik, Wu, Benjamin M., Bass, Michael B., Zhong, Zhandong D., Friberg, Greg, Rosen, Lee S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294348/ https://www.ncbi.nlm.nih.gov/pubmed/25525888 |
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