Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters

Recent studies have reported that hyper-methylation in the promoter region of miRNAs could silence the expression of tumor suppressive miRNAs and might play significant roles in the process of tumor development. However, the potential mechanisms regarding how methylation of miRNA CpG Island could re...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Yang, Zhiping, Xia, Lin, Nie, Yongzhan, Wu, Kaichun, Shi, Yongquan, Fan, Daiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294356/
https://www.ncbi.nlm.nih.gov/pubmed/25344911

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