Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

Interactions with the bone marrow microenvironment are essential for leukemia survival and disease progression. We developed an imaging-based RNAi platform to identify protective cues from bone marrow derived mesenchymal stromal cells (MSC) that promote survival of primary acute lymphoblastic leukem...

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Detalles Bibliográficos
Autores principales: Boutter, Jeannette, Huang, Yun, Marovca, Blerim, Vonderheit, Andreas, Grotzer, Michael A., Eckert, Cornelia, Cario, Gunnar, Wollscheid, Bernd, Horvath, Peter, Bornhauser, Beat C., Bourquin, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294362/
https://www.ncbi.nlm.nih.gov/pubmed/25415224

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