NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer

Despite the use of clinical prognostic factors (PSA, T-category and Gleason score), 20-60% of localized prostate cancers (PCa) fail primary local treatment. Herein, we determined the prognostic importance of main sensors of the DNA damage response (DDR): MRE11A, RAD50, NBN, ATM, ATR and PRKDC. We st...

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Detalles Bibliográficos
Autores principales: Berlin, Alejandro, Lalonde, Emilie, Sykes, Jenna, Zafarana, Gaetano, Chu, Kenneth C., Ramnarine, Varune R., Ishkanian, Adrian, Sendorek, Dorota H.S., Pasic, Ivan, Lam, Wan L., Jurisica, Igor, van der Kwast, Theo, Milosevic, Michael, Boutros, Paul C., Bristow, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4294365/
https://www.ncbi.nlm.nih.gov/pubmed/25415046

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